Rhodococcus equi Infections in Goats: Characterization of Virulence Plasmids. Academic Article

abstract

• Rhodococcus equi is an uncommon cause of systemic pyogranulomatous infections in goats with macroscopic similarities to caseous lymphadenitis caused by Corynebacterium pseudotuberculosis. Caprine cases have previously been reported to be caused by avirulent R. equi strains. Six cases of R. equi infection in goats yielding 8 R. equi isolates were identified from 2000 to 2017. Lesions varied from bronchopneumonia, vertebral and humeral osteomyelitis, and subcutaneous abscesses, to disseminated infection involving the lungs, lymph nodes, and multiple visceral organs. Isolates of R. equi from infected goats were analyzed by polymerase chain reaction for R. equi virulence-associated plasmid ( vap) genes. Seven of 8 isolates carried the VapN plasmid, originally characterized in bovine isolates, while 1 isolate lacked virulence plasmids and was classified as avirulent. The VapN plasmid has not been described in isolates cultured from goats.

authors

• Bryan, Laura
• Cohen, Noah
• Lawhon, Sara
• Stranahan, Lauren

published proceedings

• Vet Pathol

altmetric score

• 0.25

author list (cited authors)

• Stranahan, L. W., Plumlee, Q. D., Lawhon, S. D., Cohen, N. D., & Bryan, L. K.

citation count

• 22

complete list of authors

• Stranahan, Lauren W||Plumlee, Quinci D||Lawhon, Sara D||Cohen, Noah D||Bryan, Laura K

publication date

• March 2018

publisher

• SAGE Publications  Publisher

published in

• Veterinary Pathology  Journal

keywords

• Actinomycetales Infections
• Animals
• Caseous Lymphadenitis
• Goat
• Goat Diseases
• Goats
• Lung
• Lymph Nodes
• Plasmids
• Rhodococcus Equi
• Virulence Factors
• Virulence Plasmids
• Virulence-associated Protein N

PubMed Central ID

• 29254455

Digital Object Identifier (DOI)

• 10.1177/0300985817747327

start page

• 273

end page

• 276

volume

• 55

issue

• 2

URL

• http://dx.doi.org/10.1177/0300985817747327