The TB structural genomics consortium: providing a structural foundation for drug discovery. Academic Article uri icon

abstract

  • Structural genomics, the large-scale determination of protein structures, promises to provide a broad structural foundation for drug discovery. The tuberculosis (TB) Structural Genomics Consortium is devoted to encouraging, coordinating, and facilitating the determination of structures of proteins from Mycobacterium tuberculosis and hopes to determine 400 TB protein structures over 5 years. The Consortium has determined structures of 28 proteins from TB to date. These protein structures are already providing a basis for drug discovery efforts.

altmetric score

  • 1

author list (cited authors)

  • Goulding, C. W., Apostol, M., Anderson, D. H., Gill, H. S., Smith, C. V., Kuo, M. R., ... Terwilliger, T. C.

citation count

  • 66

complete list of authors

  • Goulding, Celia W||Apostol, Marcin||Anderson, Daniel H||Gill, Harindarpal S||Smith, Clare V||Kuo, Mack R||Yang, Jin Kuk||Waldo, Geoffrey S||Suh, Se Won||Chauhan, Radha||Kale, Avinash||Bachhawat, Nandita||Mande, Shekhar C||Johnston, Jodie M||Lott, J Shaun||Baker, Edward N||Arcus, Vickery L||Leys, David||McLean, Kirsty J||Munro, Andrew W||Berendzen, Joel||Sharma, Vivek||Park, Min S||Eisenberg, David||Sacchettini, James||Alber, Tom||Rupp, Bernhard||Jacobs, William||Terwilliger, Thomas C

publication date

  • June 2002