In-Vitro Dissolution Dynamic Nuclear Polarization for Sensitivity Enhancement of NMR with Biological Molecules
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Dissolution dynamic nuclear polarization (D-DNP) is a technique to prepare hyperpolarized nuclear spin states, yielding a signal enhancement of several orders of magnitude for liquid-state NMR. Here, we describe experimental procedures for the application of D-DNP in high-resolution NMR of biochemical compounds, to determine the time evolution of biochemical processes and intermolecular interactions.
author list (cited authors)
Kim, Y., Wang, Y., Chen, H., & Hilty, C.
complete list of authors
Kim, Yaewon||Wang, Yunyi||Chen, Hsueh-Ying||Hilty, Christian