An unusual case of canine osteosarcoma. Academic Article

abstract

• A spontaneous osteosarcoma in the limb of a dog had atypical histologic and ultrastructural appearances, and a hyperdyploid karyotype. Malignant cells aggregated into nodular structures, within which tumor osteoid was deposited. Tumor cells showed cytodifferentiation toward osteoblasts, with development of a relatively conspicuous rough endoplasmic reticulum and Golgi zones. Junctional contacts were commonly found between contiguous tumor cells. The finding of a hyperdyploid karyotype in component cells was in contradistinction to the reported hypodyploid state of canine osteosarcomas. Copyright 1974 American Cancer Society

authors

• Pool, Roy

published proceedings

• Cancer

author list (cited authors)

• Pool, R. R., & Wolf, H. G.

citation count

• 5

complete list of authors

• Pool, RR||Wolf, HG

publication date

• September 1974

publisher

• Wiley  Publisher

keywords

• Animals
• Chromosome Aberrations
• Dogs
• Endoplasmic Reticulum
• Golgi Apparatus
• Karyotyping
• Microscopy, Electron
• Osteosarcoma
• Tibia

Digital Object Identifier (DOI)

• 10.1002/1097-0142(197409)34:3<771::aid-cncr2820340337>3.0.co;2-v

start page

• 771

end page

• 779

volume

• 34

issue

• 3

URL

• http://dx.doi.org/10.1002/1097-0142(197409)34:3%3C771::aid-cncr2820340337%3E3.0.co;2-v