Hypoperfusion of the small intestine during slow infusion of a low dosage of endotoxin in anesthetized horses. Academic Article

abstract

• The effects of intravenous infusion of endotoxin for 30 minutes at a cumulative dosage of 0.03 micrograms/kg on average carotid arterial pressure, and on average arterial pressure, capillary pressure, venous pressure, total vascular resistance, precapillary resistance, postcapillary resistance, and capillary filtration coefficient in the jejunum were compared to the effects of intravenous infusion of 0.9% sodium chloride solution in 6 anesthetized horses. Endotoxin significantly reduced intestinal venous blood flow by inducing vasoconstriction. Increased vascular resistance resulted from increased precapillary resistance. The capillary filtration coefficient was unchanged by endotoxin. These results suggest that intestinal vasoconstriction occurs during the compensatory stages of endotoxemia.

authors

• Eades, Erma

published proceedings

• Cornell Vet

author list (cited authors)

• Clark, E. S., & Collatos, C.

citation count

• 7

complete list of authors

• Clark, ES||Collatos, C

publication date

• April 1990

published in

• The Cornell veterinarian  Journal

keywords

• Animals
• Blood Pressure
• Capillary Resistance
• Endotoxins
• Horse Diseases
• Horses
• Infusions, Intravenous
• Jejunum
• Regional Blood Flow
• Vascular Resistance
• Vasoconstriction

PubMed Central ID

• 2318042

start page

• 163

end page

• 172

volume

• 80

issue

• 2