Equine infectious anemia virus replication is upregulated during differentiation of blood monocytes from acutely infected horses. Academic Article

abstract

• Equine infectious anemia virus is a lentivirus that replicates in mature tissue macrophages of horses. Ponies were infected with equine infectious anemia virus. During febrile episodes, proviral DNA was detectable, but viral mRNA was not detectable. As cultured blood monocytes from these ponies differentiated into macrophages, viral expression was upregulated. In situ hybridization confirmed that viral transcription occurred in mature macrophages.

authors

• Russell, Karen

published proceedings

• J Virol

author list (cited authors)

• Sellon, D. C., Walker, K. M., Russell, K. E., Perry, S. T., Covington, P., & Fuller, F. J.

citation count

• 18

complete list of authors

• Sellon, DC||Walker, KM||Russell, KE||Perry, ST||Covington, P||Fuller, FJ

publication date

• January 1996

publisher

• American Society for Microbiology  Publisher

published in

• Journal of Virology  Journal

keywords

• Acute Disease
• Animals
• Cell Differentiation
• DNA, Viral
• Equine Infectious Anemia
• Horses
• Infectious Anemia Virus, Equine
• Monocytes
• RNA, Messenger
• RNA, Viral
• Up-Regulation
• Virus Replication

Digital Object Identifier (DOI)

• 10.1128/JVI.70.1.590-594.1996

start page

• 590

end page

• 594

volume

• 70

issue

• 1

URL

• http://dx.doi.org/10.1128/jvi.70.1.590-594.1996

user-defined tag

• 3 Good Health and Well-Being