Equine infectious anemia virus replication is upregulated during differentiation of blood monocytes from acutely infected horses. Academic Article uri icon


  • Equine infectious anemia virus is a lentivirus that replicates in mature tissue macrophages of horses. Ponies were infected with equine infectious anemia virus. During febrile episodes, proviral DNA was detectable, but viral mRNA was not detectable. As cultured blood monocytes from these ponies differentiated into macrophages, viral expression was upregulated. In situ hybridization confirmed that viral transcription occurred in mature macrophages.

published proceedings

  • J Virol

author list (cited authors)

  • Sellon, D. C., Walker, K. M., Russell, K. E., Perry, S. T., Covington, P., & Fuller, F. J.

citation count

  • 18

complete list of authors

  • Sellon, DC||Walker, KM||Russell, KE||Perry, ST||Covington, P||Fuller, FJ

publication date

  • January 1996