World Health Organization Ranking of Antimicrobials According to Their Importance in Human Medicine: A Critical Step for Developing Risk Management Strategies to Control Antimicrobial Resistance From Food Animal Production. Academic Article uri icon


  • Antimicrobial use in food animals selects for antimicrobial resistance in bacteria, which can spread to people. Reducing use of antimicrobials-particularly those deemed to be critically important for human medicine-in food production animals continues to be an important step for preserving the benefits of these antimicrobials for people. The World Health Organization ranking of antimicrobials according to their relative importance in human medicine was recently updated. Antimicrobials considered the highest priority among the critically important antimicrobials were quinolones, third- and fourth-generation cephalosporins, macrolides and ketolides, and glycopeptides. The updated ranking allows stakeholders in the agriculture sector and regulatory agencies to focus risk management efforts on drugs used in food animals that are the most important to human medicine. In particular, the current large-scale use of fluoroquinolones, macrolides, and third-generation cephalosporins and any potential use of glycopeptides and carbapenems need to be addressed urgently.

published proceedings

  • Clin Infect Dis

altmetric score

  • 56.65

author list (cited authors)

  • Collignon, P. J., Conly, J. M., Andremont, A., McEwen, S. A., Aidara-Kane, A., World Health Organization Advisory Group, Bogot Meeting on Integrated Surveillance of Antimicrobial Resistance (WHO-AGISAR), .., ... Woo, G.

citation count

  • 158

complete list of authors

  • Collignon, Peter J||Conly, John M||Andremont, Antoine||McEwen, Scott A||Aidara-Kane, Awa||Agerso, Yvonne||Andremont, Antoine||Collignon, Peter||Conly, John||Dang Ninh, Tran||Donado-Godoy, Pilar||Fedorka-Cray, Paula||Fernandez, Heriberto||Galas, Marcelo||Irwin, Rebecca||Karp, Beth||Matar, Gassan||McDermott, Patrick||McEwen, Scott||Mitema, Eric||Reid-Smith, Richard||Scott, H Morgan||Singh, Ruby||DeWaal, Caroline Smith||Stelling, John||Toleman, Mark||Watanabe, Haruo||Woo, Gun-Jo

editor list (cited editors)

  • Griffin, P. M.

publication date

  • October 2016