Influence of palmitic acid on mouse lymphocyte function in vivo and in vitro. Academic Article

abstract

• The effect of palmitic acid on the immune response of mice to sheep erythrocytes was studied. It was found to increase the number of background plaques in normal mice but it had no significant effect on primed cells. When given with antigen it functioned as a weak adjuvant but it had no effect on response of mouse lymphocytes to the mitogens phytohemagglutinin or bacterial lipopolysaccharide. While it is clear that palmitic acid does not have a profound effect on lymphocyte reactivity, it may have a subtle modulating influence on the immune system.

authors

• Tizard, Ian

published proceedings

• Int Arch Allergy Appl Immunol

author list (cited authors)

• Tizard, I., & Sheppard, J.

citation count

• 4

complete list of authors

• Tizard, I||Sheppard, J

publication date

• January 1982

publisher

• Karger Publishers  Publisher

published in

• International Archives of Allergy and Applied Immunology  Journal

keywords

• Adjuvants, Immunologic
• Animals
• Antibody Formation
• Antigens
• Erythrocytes
• Female
• In Vitro Techniques
• Lymphocyte Activation
• Lymphocytes
• Mice
• Mitogens
• Palmitic Acid
• Palmitic Acids
• Sheep

PubMed Central ID

• 7061149

Digital Object Identifier (DOI)

• 10.1159/000233018

start page

• 197

end page

• 199

volume

• 67

issue

• 3

URL

• http://dx.doi.org/10.1159/000233018