Chromosomal location of soluble glutamic-pyruvic transaminase-1 (Gpt-1) in the mouse. Academic Article

abstract

• Three alleles at the Gpt-1 (glutamic-pyruvic transaminase-1) locus in the mouse, as identified by electrophoresis on cellulose acetate, and their distribution among inbred mouse strains and wild stocks are described. The Gpt-1 locus was shown to control the soluble form of the enzyme. Three-point linkage analysis established th location of Gpt-1 on chromosome 15 between uw and bt. In addition, a new staining procedure is described that allows the visualization of GPT activity on gels by the deposition of formazan. This is an improvement over previous methods that produced bands of nonfluorescence against a fluorescent background.

authors

• Womack, James

published proceedings

• Biochem Genet

author list (cited authors)

• Eicher, E. M., & Womack, J. E.

citation count

• 23

complete list of authors

• Eicher, EM||Womack, JE

publication date

• February 1977

publisher

• Springer Nature  Publisher

published in

• Biochemical Genetics  Journal

keywords

• Alanine Transaminase
• Alleles
• Animals
• Chromosome Mapping
• Crosses, Genetic
• Female
• Formazans
• Genes
• Genetic Linkage
• Liver
• Male
• Mice
• Mice, Inbred Strains
• Polymorphism, Genetic

Digital Object Identifier (DOI)

• 10.1007/BF00484544

start page

• 1

end page

• 8

volume

• 15

issue

• 1-2

URL

• http://dx.doi.org/10.1007/bf00484544