Surface functionalization of porous coordination nanocages via click chemistry and their application in drug delivery. Academic Article

abstract

• Porous coordination nanocages covered with alkyne groups are synthesized through judicious selection of the ligand and reaction conditions. The surface functionalization via click reaction with azide-terminated polyethylene glycol turns them into water-stable colloids, which exhibit controlled release of an anticancer drug 5-fluorouracil. Copyright 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

authors

• Zhou, Hongcai

published proceedings

• Adv Mater

author list (cited authors)

• Zhao, D., Tan, S., Yuan, D., Lu, W., Rezenom, Y. H., Jiang, H., Wang, L., & Zhou, H.

citation count

• 303

complete list of authors

• Zhao, Dan||Tan, Songwei||Yuan, Daqiang||Lu, Weigang||Rezenom, Yohannes H||Jiang, Hongliang||Wang, Li-Qun||Zhou, Hong-Cai

publication date

• January 2011

publisher

• Wiley  Publisher

published in

• ADVANCED MATERIALS  Journal

keywords

• Antimetabolites, Antineoplastic
• Click Chemistry
• Delayed-Action Preparations
• Fluorouracil
• Nanocapsules
• Porosity
• Surface Properties

PubMed Central ID

• 20972982

Digital Object Identifier (DOI)

• 10.1002/adma.201003012

start page

• 90

end page

• 93

volume

• 23

issue

• 1

URL

• http://dx.doi.org/10.1002/adma.201003012