The Pinholin of Lambdoid Phage 21: Control of Lysis by Membrane Depolarization▿ Academic Article uri icon

abstract

  • The phage 21 holin, S(21), forms small membrane holes that depolarize the membrane and is designated as a pinholin, as opposed to large-hole-forming holins, like S(lambda). Pinholins require secreted SAR endolysins, a pairing that may represent an intermediate in the evolution of canonical holin-endolysin systems.

author list (cited authors)

  • Park, T., Struck, D. K., Dankenbring, C. A., & Young, R. y.

citation count

  • 62

publication date

  • September 2007