Novel application of the intramolecular Prins reaction: (-)-anisatin model study
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abstract
Hydrolysis of the enol ethers 9a and 9b gave the aldehyde 10 which cyclized in situ to the alcohols lia and lib via an intramolecular Prins reaction. Further regio- and stereocontrolled elaboration of the alcohols lia and lib afforded the lactone diol 14.