The Effects of the [latin sharp s]2-Agonist Clenbuterol, and Exercise Training on Muscle Protein and Performance in Frogs. Academic Article uri icon


  • The effects of exercise training and clenbuterol on the exercise performance and muscle morphology of 69 adult male Northern grass frogs were compared. Frogs were randomly assigned to 1 of 4 groups: control (C), exercise (Ex), drug (Dr), and exercise + drug (Ex + Dr). Groups were tested before and after 6 weeks of treadmill training to evaluate treadmill exercise capacity (no. of hops) and force production during jumps. Data were analyzed with one-way MANOVAs (p < 0.05). Ex performed more hops than the other groups. In regard to force output, however, that of Dr was significantly greater that that of the other groups. For gastrocnemius weight, that of C was significantly less than for the other groups while that of Dr was significantly greater than Ex and Ex + Dr. Total muscle protein content showed no significant differences; myofibrillar protein content showed that Ex and Dr, though not significantly different from each other, were superior to C and Ex + Dr. This may suggest that clenbuterol and exercise, when combined, may impede muscle growth and performance. 1996 Lippincott Williams & Wilkins, Inc.

published proceedings

  • The Journal of Strength and Conditioning Research

author list (cited authors)

  • Willoughby, D. S., Barnes, W. S., Ingalls, C. P., & Smith, S. B.

citation count

  • 2

complete list of authors

  • Willoughby, Darryn S||Barnes, William S||Ingalls, Chris P||Smith, Stephen B

publication date

  • January 1996