Increased X-ray Visualization of Shape Memory Polymer Foams by Chemical Incorporation of Iodine Motifs. Academic Article uri icon

abstract

  • Shape memory polymers can be programmed into a secondary geometry and recovered to their primary geometry with the application of a controlled stimulus. Porous shape memory polymer foam scaffolds that respond to body temperature show particular promise for embolic medical applications. A limitation for the minimally invasive delivery of these materials is an inherent lack of X-ray contrast. In this work, a triiodobenzene containing a monomer was incorporated into a shape memory polymer foam material system to chemically impart X-ray visibility and increase material toughness. Composition and process changes enabled further control over material density and thermomechanical properties. The proposed material system demonstrates a wide range of tailorable functional properties for the design of embolic medical devices, including X-ray visibility, expansion rate, and porosity. Enhanced visualization of these materials can improve the acute performance of medical devices used to treat vascular malformations, and the material porosity provides a healing scaffold for durable occlusion.

published proceedings

  • Polymers (Basel)

altmetric score

  • 6.75

author list (cited authors)

  • Nash, L. D., Browning Monroe, M. B., Ding, Y., Ezell, K. P., Boyle, A. J., Kadirvel, R., Kallmes, D. F., & Maitland, D. J.

citation count

  • 10

complete list of authors

  • Nash, Landon D||Browning Monroe, Mary Beth||Ding, Yong-Hong||Ezell, Kendal P||Boyle, Anthony J||Kadirvel, Ramanathan||Kallmes, David F||Maitland, Duncan J

publication date

  • August 2017