RutA-Catalyzed Oxidative Cleavage of the Uracil Amide Involves Formation of a Flavin-N5-oxide. Academic Article

abstract

• RutA is a novel flavoenzyme on the uracil catabolic pathway that catalyzes uracil ring opening by a unique amide oxidation reaction. Here we provide evidence that this reaction also involves the formation of a flavin-N5-oxide.

authors

• Begley, Tadhg

published proceedings

• Biochemistry

author list (cited authors)

• Adak, S., & Begley, T. P.

citation count

• 26

complete list of authors

• Adak, Sanjoy||Begley, Tadhg P

publication date

• July 2017

publisher

• American Chemical Society (ACS)  Publisher

published in

• Biochemistry  Journal

keywords

• Catalysis
• Dinitrocresols
• Models, Chemical
• Polyenes
• Uracil

PubMed Central ID

• 28661684

Digital Object Identifier (DOI)

• 10.1021/acs.biochem.7b00493

start page

• 3708

end page

• 3709

volume

• 56

issue

• 29

URL

• http://dx.doi.org/10.1021/acs.biochem.7b00493