Flavin-N5-oxide: A new, catalytic motif in flavoenzymology Academic Article uri icon


  • Flavin-N5-oxide is a recently discovered intermediate used by EncM (1,3-diketone oxidation), DszA (sulfone monooxygenase) and RutA (amide monooxygenase). This review describes the mechanism of these enzymes and proposes criteria for the identification of additional Flavin-N5-oxide dependent enzymes.

author list (cited authors)

  • Adak, S., & Begley, T. P.

citation count

  • 12

publication date

  • August 2017