Flavin-N5-oxide: A new, catalytic motif in flavoenzymology. Academic Article

abstract

• Flavin-N5-oxide is a recently discovered intermediate used by EncM (1,3-diketone oxidation), DszA (sulfone monooxygenase) and RutA (amide monooxygenase). This review describes the mechanism of these enzymes and proposes criteria for the identification of additional Flavin-N5-oxide dependent enzymes.

authors

• Begley, Tadhg

published proceedings

• Arch Biochem Biophys

author list (cited authors)

• Adak, S., & Begley, T. P.

citation count

• 19

complete list of authors

• Adak, Sanjoy||Begley, Tadhg P

publication date

• January 2017

publisher

• Elsevier  Publisher

published in

• Archives of Biochemistry and Biophysics  Journal

keywords

• Amino Acid Motifs
• Catalysis
• Flavins
• Flavoproteins
• Mixed Function Oxygenases

Digital Object Identifier (DOI)

• 10.1016/j.abb.2017.08.001

start page

• 4

end page

• 10

volume

• 632

URL

• http://dx.doi.org/10.1016/j.abb.2017.08.001