Listeric meningoencephalitis in goats. Academic Article uri icon


  • A neurologic disease was observed in three young adult goats (indentified as A-C) from a herd of 100 goats during October-December, 2004. Clinical signs included head tilt, torticollis, nystagmus, staggering, falls and eventually recumbency and paddling, with stiff limbs. Treatment of Goat C with antibiotics resulted in a temporary remission of the clinical signs. The clinical courses where 5, 10 and 30 days respectively for Goats A, B and C. Goat A died spontaneously and the other two where euthanatized in extremis. No gross changes were observed. Histologic lesions were predominantly unilateral, with inflammatory and degenerative changes, extending from the medulla oblongata to the thalamus. In all 3 cases there were perivascular cuffings of one or more types of mononuclear cells (lymphocytes, plasma cells, activated macrophages) and occasionally neutrophils associated with areas of malacia where Gitter cells filled spaces of parenchymal loss. Additionally, Goat B had microabscesses in the medulla, pons, and mesencephalon and multifocal neutrophilic and lymphocytic infiltrates within the fascicles of the trigeminal nerve and in the cerebellar leptomeninges. In the brainstem of Goat C, there was multifocal granulomatous inflammation which included epithelioid macrophages and occasional multinucleated giant cells. Listeria sp antigen was detected by imunohistochemistiy in routinely processed sections of mesencephalon from Goats A and C and of pons from Goat B.

published proceedings


author list (cited authors)

  • Rissi, D. R., Rech, R. R., Barros, R. R., Kommers, G. D., Langohr, I. M., Pierezan, F., & Barros, C.

citation count

  • 18

complete list of authors

  • Rissi, DR||Rech, RR||Barros, RR||Kommers, GD||Langohr, IM||Pierezan, F||Barros, CSL

publication date

  • January 2006