Coronary smooth muscle and endothelial adaptations to exercise training. Academic Article uri icon

abstract

  • Exercise training produces complex changes in intrinsic control of coronary vascular resistance. In smooth muscle, adaptations that alter Ca2+ regulation seem central, including changes in the function of sarcolemmal K+ and L-type Ca2+ channels and the sarcoplasmic reticulum. Exercise training also increases the ability of the endothelium to release vasoactive factors, with increased expression and activity of endothelial cell nitric oxide synthase playing a key role.

published proceedings

  • Exerc Sport Sci Rev

author list (cited authors)

  • Bowles, D. K., Woodman, C. R., & Laughlin, M. H

citation count

  • 38

complete list of authors

  • Bowles, DK||Woodman, CR||Laughlin, MH

publication date

  • April 2000