It has long been accepted that cracking of hot-mix asphalt (HMA) pavements is a major mode of premature failure. Many state departments of transportation have verified that pavement cracking occurred not only in fatigue cracking in which a crack initiates from the bottom of the asphalt layer but also in other modes such as low-temperature cracking and the more recently identified top-down cracking. Recent work at the University of Florida has led to the development of a crack growth law based on viscoelastic fracture mechanics that is capable of fully describing both initiation and propagation of cracks in asphalt mixtures. The model requires the determination of only four fundamental mixture parameters, which can be obtained from less than 1 h of testing using the Superpave® indirect tensile test (IDT). These parameters can account for microdamage, crack propagation, and healing for stated loading conditions, temperatures, and rest periods. The generalization of the HMA crack growth law needed for its successful implementation into a displacement discontinuity boundary element method is described. The resulting HMA boundary element approach is shown to predict the crack propagation of two coarse-graded mixtures under cyclic IDT loading conditions.