The gene controlling the binding sites of Dolichos biflorus agglutinin, Dlb-1, is on chromosome 11 of the mouse. Academic Article uri icon

abstract

  • SUMMARYA locus, Dlb-1, controlling the binding of the lectin from Dolichos biflorus to the intestinal epithelium and vascular endothelium of mice has been located on chromosome 11, 3.1 1.4 centimorgans proximal to Rex, using recombinant inbred strains and conventional backcrosses with three-point linkage tests.The two alleles so far discovered at this locus behave unusually. The Dlb-1a allele causes binding to the vascular endothelium but not to the intestinal epithelium while Dlb-1b induces the exact reciprocal binding pattern, and the heterozygote shows both patterns.

published proceedings

  • Genet Res

author list (cited authors)

  • Uiterdijk, H. G., Ponder, B. A., Festing, M. F., Hilgers, J., Skow, L., & Van Nie, R.

citation count

  • 17

complete list of authors

  • Uiterdijk, HG||Ponder, BA||Festing, MF||Hilgers, J||Skow, L||Van Nie, R

publication date

  • April 1986