Synovitis associated with serum IgM rheumatoid factor arising spontaneously in 'Old English' rabbits. Academic Article

abstract

• This paper reports the spontaneous development of synovitis in 'Old English' rabbits concurrent with serum IgM rheumatoid factor. Female rabbits developed lesions at a higher incidence than males (42% compared with 17%) and the pathology was of a more severe nature. In the female rabbits synovitis was associated with concurrent high serum IgM rheumatoid factor and high serum antibody levels to Pasteurella multocida. There was no histological evidence that the joints were directly infected.

authors

• Welsh, Christabel Jane

published proceedings

• Ann Rheum Dis

author list (cited authors)

• Hanglow, A. C., Welsh, C. J., Conn, P., Thomas, D. S., & Coombs, R. R.

citation count

• 4

complete list of authors

• Hanglow, AC||Welsh, CJ||Conn, P||Thomas, DS||Coombs, RR

publication date

• April 1986

publisher

• BMJ  Publisher

published in

• ANNALS OF THE RHEUMATIC DISEASES  Journal

keywords

• Animals
• Antigen-Antibody Complex
• Autoantibodies
• Collagen
• Complement Activating Enzymes
• Complement C1q
• Immunoglobulin M
• Pasteurella
• Rabbits
• Rheumatoid Factor
• Synovial Fluid
• Synovitis

PubMed Central ID

• 3486640

Digital Object Identifier (DOI)

• 10.1136/ard.45.4.331

start page

• 331

end page

• 338

volume

• 45

issue

• 4

URL

• http://dx.doi.org/10.1136/ard.45.4.331