Early rheumatoid-like synovial lesions in rabbits drinking cow's milk. I. Joint pathology. Academic Article

abstract

• Rheumatoid-like lesions developed in 9 of 25 (36%) Old English rabbits drinking cow's milk for 12 weeks. The incidence of lesions in male and female animals was similar. The majority of rabbits drinking cow's milk developed increased numbers of nucleated cells and raised percentages of T lymphocytes in their synovial fluids, compared to control rabbits. The cell counts and T cell percentages correlated with the severity of the histological lesions. No evidence of glomerulonephritis was observed in any of the experimental animals.

authors

• Welsh, Christabel Jane

published proceedings

• Int Arch Allergy Appl Immunol

author list (cited authors)

• Welsh, C. J., Hanglow, A. C., Conn, P., Barker, T. H., & Coombs, R. R.

citation count

• 14

complete list of authors

• Welsh, CJ||Hanglow, AC||Conn, P||Barker, TH||Coombs, RR

publication date

• January 1985

publisher

• Karger Publishers  Publisher

published in

• International Archives of Allergy and Applied Immunology  Journal

keywords

• Animals
• Arthritis, Rheumatoid
• Cartilage, Articular
• Cattle
• Disease Models, Animal
• Female
• Kidney
• Male
• Milk
• Neutrophils
• Plasma Cells
• Rabbits
• Synovial Fluid
• T-Lymphocytes

Digital Object Identifier (DOI)

• 10.1159/000233877

start page

• 145

end page

• 151

volume

• 78

issue

• 2

URL

• http://dx.doi.org/10.1159/000233877