Comparison of coherent and spontaneous Raman microspectroscopies for noninvasive detection of single bacterial endospores. Academic Article uri icon


  • Single bacterial spores were analyzed by using nonlinear Raman microspectroscopy based on coherent anti-Stokes Raman scattering (CARS). The Raman spectra were retrieved from CARS spectra and found to be in excellent agreement with conventionally collected Raman spectra. The phase retrieval method based on maximum entropy model revealed significant robustness to external noise. The direct comparison of signal amplitudes exhibited a factor of 100 stronger CARS signal, as compared with the Raman signal.

published proceedings

  • Proc Natl Acad Sci U S A

author list (cited authors)

  • Petrov, G. I., Arora, R., Yakovlev, V. V., Wang, X. i., Sokolov, A. V., & Scully, M. O.

citation count

  • 130

complete list of authors

  • Petrov, Georgi I||Arora, Rajan||Yakovlev, Vladislav V||Wang, Xi||Sokolov, Alexei V||Scully, Marlan O

publication date

  • May 2007