Development and applications of transgenesis in the yellow fever mosquito, Aedes aegypti. Academic Article

abstract

• Transgenesis technology has been developed for the yellow fever mosquito, Aedes aegypti. Successful integration of exogenous DNA into the germline of this mosquito has been achieved with the class II transposable elements, Hermes, mariner and piggyBac. A number of marker genes, including the cinnabar(+) gene of Drosophila melanogaster, and fluorescent protein genes, can be used to monitor the insertion of these elements. The availability of multiple elements and marker genes provides a powerful set of tools to investigate basic biological properties of this vector insect, as well as the materials for developing novel, genetics-based, control strategies for the transmission of disease.

authors

• Adelman, Zachary

published proceedings

• Mol Biochem Parasitol

altmetric score

• 6

author list (cited authors)

• Adelman, Z. N., Jasinskiene, N., & James, A. A.

citation count

• 44

complete list of authors

• Adelman, Zachary N||Jasinskiene, Nijole||James, Anthony A

publication date

• January 2002

publisher

• Elsevier  Publisher

published in

• Molecular and Biochemical Parasitology  Journal

keywords

• Aedes
• Animals
• Animals, Genetically Modified
• DNA Transposable Elements
• Genetic Markers
• Humans
• Insect Vectors
• Mosquito Control
• Mutagenesis, Insertional
• Yellow Fever

Digital Object Identifier (DOI)

• 10.1016/s0166-6851(02)00028-2

start page

• 1

end page

• 10

volume

• 121

issue

• 1

URL

• http://dx.doi.org/10.1016/s0166-6851(02)00028-2