Tuning of Luminescent Sensor Response and Degradation through Manipulation of Nanofilm Coating Properties
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Enzymatic glucose sensors based on luminescent microparticles rely on the reaction of glucose and oxygen with glucose oxidase, where the internal oxygen level is transduced via oxygen-sensitive phosphors. These sensors utilize nanofilm coatings comprising polyelectrolyte multilayers deposited using self-assembly to control transport of glucose, enabling tuning of the range and sensitivity by changing the coating thickness. In this work, it was also found that salt concentrations, which influence thickness and density of nanofilm coatings during multilayer deposition, also influence range, sensitivity, and degradation rate of these sensors. 2010 IEEE.