Glucose micro- and nano-sensors based on nanoassembled enzyme/polymer/dye composites Conference Paper

abstract

• Minimally-invasive glucose sensors are attractive for disease management as well as medical and biological research applications. Fluorescent sensors, coupling enzymes to catalyze specific reactions with glucose, have been developed for this purpose. Our work has focused on the downscaling of these technologies to the micro- and nano-scale by using self-assembly to build the sensing components of the assays. Both "solid" polymers and hollow microshells have been developed to physically couple the sensing materials together in biocompatible, semipermeable packages suitable for use in biological systems. Fabrication details and sensor characterization are used to demonstrate the potential of these sensor concepts.

name of conference

• Optical Diagnostics and Sensing IV

authors

• McShane, Michael

published proceedings

• OPTICAL DIAGNOSTICS AND SENSING IV

author list (cited authors)

• Brown, J. Q., Chopra, S., Grant, P. S., & McShane, M. J.

citation count

• 3

complete list of authors

• Brown, JQ||Chopra, S||Grant, PS||McShane, MJ

editor list (cited editors)

• Cote, G. L., & Priezzhev, A. V.

publication date

• January 2004

publisher

• SPIE, the international society for optics and photonics  Publisher

published in

• Proceedings of SPIE  Journal

keywords

• Biosensors
• FLUORESCENCE
• Glucose Sensing
• Microspheres
• Nanoassembly
• Nanoparticles
• Self-assembly

Digital Object Identifier (DOI)

• 10.1117/12.529797

International Standard Book Number (ISBN) 10

• 0-8194-5233-5

start page

• 21

end page

• 30

volume

• 5325