Fabrication of a biosensor with embedded waveguides for sensing in microchannels Academic Article

abstract

• The fabrication and testing of a novel waveguide based biosensor for sensing in microchannels is presented. Unlike evanescent wave sensing, which has large intrinsic losses, an absorption based sensing scheme was introduced. The fabricated waveguide sensor has excellent transparency in the UV-Vis region of the spectra and is able to perform simultaneous detection of multiple analytes in microchannels. The optical interconnection to the device was achieved using self-aligned V-grooves etched on the silicon wafer using KOH etching. The fabricated device has applications in micro total analysis systems for measuring various analytes in the microchannels, tissue engineering for continuous measurement of the oxygen in the artificial scaffolds, and fluorescence-based measurement by attaching fluorescent dyes to the waveguide end face in the microchannel.

authors

• McShane, Michael

published proceedings

• SECOND JOINT EMBS-BMES CONFERENCE 2002, VOLS 1-3, CONFERENCE PROCEEDINGS

author list (cited authors)

• Deverkadra, R. R., & McShane, M. J.

citation count

• 3

complete list of authors

• Deverkadra, RR||McShane, MJ

publication date

• January 2002

publisher

• Institute of Electrical and Electronics Engineers (IEEE)  Publisher

published in

• 2015 37TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)  Journal

keywords

• Biosensor
• Micro Total Analysis System
• Microchannel
• PMMA
• V-grooves
• Waveguides

Digital Object Identifier (DOI)

• 10.1109/iembs.2002.1106619

start page

• 1720

end page

• 1721

volume

• 2

URL

• http://dx.doi.org/10.1109/iembs.2002.1106619