Self-assembly of Surfactant-like Peptides with Variable Glycine Tails to Form Nanotubes and Nanovesicles Academic Article uri icon


  • The self-assembly of surfactant-like peptides containing 4-10 glycines as the component of the hydrophobic tails and aspartic acids as the hydrophilic heads is described. The peptide monomers form nanotubes and nanovesicles in water at neutral pH. These nanostructures become more polydisperse as the length of the glycine tails increases. These unique structures may serve not only as scaffolds for constructing diverse nanodevices but also as enclosures to encapsulate rudimentary enzymes for studying prebiotic molecular evolution.

published proceedings

  • Nano Letters

altmetric score

  • 9

author list (cited authors)

  • Santoso, S., Hwang, W., Hartman, H., & Zhang, S.

citation count

  • 300

complete list of authors

  • Santoso, Steve||Hwang, Wonmuk||Hartman, Hyman||Zhang, Shuguang

publication date

  • July 2002