Laser Polarimetry For Glucose Monitoring Conference Paper uri icon

abstract

  • The optical bench prototype of a unique optical polarimetry system which could be used as a sensor to monitor in vivo glucose concentrations is described. Preliminary in vitro results are given which show the ability of the sensor to measure glucose concentrations at physiologic levels. The voltage output of the system, which is proportional to the rotation of the polarized light through the sample, is shown to be linearly related to the glucose concentration over the range from 45-300 mg/dl. It is anticipated that since an approximate signal-to-noise ratio of 20 dB was achievable with this system for a 10-cm path length sample, this method of measuring physiologic glucose concentration will have the sensitivity, with the use of additional averaging and filtering techniques, to reach the required rotations for path lengths on the order of 1 cm.

name of conference

  • [1990] Proceedings of the Twelfth Annual International Conference of the IEEE Engineering in Medicine and Biology Society

published proceedings

  • Proceedings of the Annual Conference on Engineering in Medicine and Biology

author list (cited authors)

  • Cote, G. L., Fox, M. D., & Northrop, R. B.

citation count

  • 8

complete list of authors

  • Cote, GL||Fox, MD||Northrop, RB

publication date

  • January 1990