Biosynthesis of 11 -hydroxyandrostenedione by human and baboon adrenals. Academic Article

abstract

• ABSTRACT The conversion of androstenedione and cortisol to 11-hydroxyandrostenedione was studied by in vitro incubations of human and baboon adrenals and by in vivo perfusion of baboon adrenals. By both approaches, androstenedione appeared to be the major precursor. Some sidechain cleavage of cortisol also occurs during incubation with whole blood.

authors

• Kraemer, Duane

published proceedings

• Acta Endocrinol (Copenh)

author list (cited authors)

• Axelrod, L. R., Kraemer, D. C., Burdett, J., & Goldzieher, J. W.

citation count

• 26

complete list of authors

• Axelrod, LR||Kraemer, DC||Burdett, J||Goldzieher, JW

publication date

• January 1973

publisher

• Oxford University Press (OUP)  Publisher

published in

• Acta Endocrinologica  Journal

keywords

• 17-ketosteroids
• Adrenal Glands
• Androstenes
• Animals
• Carbon Isotopes
• Chromatography, Paper
• Female
• Haplorhini
• Humans
• Hydrocortisone
• Hydroxysteroids
• In Vitro Techniques
• Papio
• Perfusion
• Tritium

Digital Object Identifier (DOI)

• 10.1530/acta.0.0720545

start page

• 545

end page

• 550

volume

• 72

issue

• 3

URL

• http://dx.doi.org/10.1530/acta.0.0720545