Pathophysiology and treatment of neuropathic pain associated with syringomyelia. Academic Article

abstract

• The pain behaviour expressed by dogs with syringomyelia suggests that they experience neuropathic pain, probably due to disordered neural processing in the damaged dorsal horn. As such it is likely that conventional analgesic medication will be ineffective. In this review, physiological and pathological pain processing through the dorsal horn is summarised and mechanisms by which syringomyelia could result in a persistent pain state are discussed. Finally, current knowledge regarding treatment of Chiari malformation and syringomyelia is reviewed and possible drugs which may give improved pain relief in affected dogs are discussed.

authors

• Jeffery, Nicholas

published proceedings

• Vet J

author list (cited authors)

• Rusbridge, C., & Jeffery, N. D.

citation count

• 72

complete list of authors

• Rusbridge, Clare||Jeffery, Nick D

publication date

• February 2008

publisher

• Elsevier  Publisher

published in

• The Veterinary Journal  Journal

keywords

• Animals
• Dog Diseases
• Dogs
• Pain
• Pain Management
• Syringomyelia

PubMed Central ID

• 17317245

Digital Object Identifier (DOI)

• 10.1016/j.tvjl.2006.12.007

start page

• 164

end page

• 172

volume

• 175

issue

• 2

URL

• http://dx.doi.org/10.1016/j.tvjl.2006.12.007