Canine lymphomatoid granulomatosis: an immunophenotypic analysis of three cases. Academic Article

abstract

• Three dogs had a history of multiple progressive lesions affecting the skin, subcutis or skeletal muscles. The lesions developed over a period of several months, and each case demonstrated late cardiopulmonary complications. Post-mortem examination revealed multicentric, angio-destructive, lymphohistiocytic, proliferative lesions typical of the rare disorder lymphomatoid granulomatosis. Immunohistochemical examination demonstrated variable CD3 antigen expression by the atypical cell population in two of the three cases. This provides the first evidence that canine lymphomatoid granulomatosis may be a form of atypical T-cell lymphoma similar to the comparable disorder that occurs in man.

authors

• Jeffery, Nicholas

published proceedings

• J Comp Pathol

author list (cited authors)

• Smith, K. C., Day, M. J., Shaw, S. C., Littlewood, J. D., & Jeffery, N. D.

citation count

• 28

complete list of authors

• Smith, KC||Day, MJ||Shaw, SC||Littlewood, JD||Jeffery, ND

publication date

• January 1996

publisher

• Elsevier  Publisher

published in

• JOURNAL OF COMPARATIVE PATHOLOGY  Journal

keywords

• Animals
• Cd3 Complex
• Connective Tissue Diseases
• Dogs
• Female
• Immunohistochemistry
• Immunophenotyping
• Lymphomatoid Granulomatosis
• Skin Diseases

PubMed Central ID

• 8910741

Digital Object Identifier (DOI)

• 10.1016/s0021-9975(96)80035-1

start page

• 129

end page

• 138

volume

• 115

issue

• 2

URL

• http://dx.doi.org/10.1016/s0021-9975(96)80035-1