Monte Carlo simulations of arterial imaging with optical coherence tomography Conference Paper uri icon

abstract

  • The laser-tissue interaction code LATIS is used to analyze photon scattering histories representative of optical coherence tomography (OCT) experiments performed at Lawrence Livermore National Laboratory. Monte Carlo photonics with Henyey-Greenstein anisotropic scattering is implemented and used to simulate signal discrimination of intravascular structure. An analytic model is developed and used to obtain a scaling law for optimization of the OCT signal and to validate Monte Carlo photonics. The appropriateness of the Henyey-Greenstein phase function is studied by direct comparison with more detailed Mie scattering theory using an ensemble of spherical dielectric scatterers. Modest differences are found between the two prescriptions for describing photon angular scattering in tissue. In particular, the Mie scattering phase functions provide less overall reflectance signal but more signal contrast compared to the Henyey-Greenstein formulation.

published proceedings

  • Proceedings of SPIE - The International Society for Optical Engineering

author list (cited authors)

  • Amendt, P., Estabrook, K., Everett, M., London, R. A., Maitland, D., Zimmerman, G., ... Sathyam, U.

complete list of authors

  • Amendt, P||Estabrook, K||Everett, M||London, RA||Maitland, D||Zimmerman, G||Colston, B||Da Silva, L||Sathyam, U

publication date

  • January 2000