Endotoxaemia in dairy cattle: mechanism of reticulorumen stasis. Academic Article

abstract

• The objective of this study was to determine whether blockade of alpha(-2) adrenergic receptors would restore reticulorumen motility during toxaemia in cows. Reticulorumen contractions were measured via a water-filled balloon connected to a pressure transducer. Intravenous infusion of endotoxin (100 ng kg-1 over 30 min) significantly decreased the number of reticulorumen contractions. Intravenous infusion of yohimbine (125 micrograms kg-1 over 30 min) alone did not affect reticulorumen contractions. However, when yohimbine (125 micrograms kg-1 over 30 min) was infused concurrently with endotoxin (100 ng kg-1 over 30 min), the effects of endotoxin on reticulorumen contraction frequency decreased, suggesting that endotoxaemia causes reticulorumen stasis via a mechanism that involves alpha(-2) adrenergic receptors.

authors

• Eades, Erma

published proceedings

• Vet J

author list (cited authors)

• Eades, S. C.

citation count

• 7

complete list of authors

• Eades, SC

publication date

• January 1997

publisher

• Elsevier  Publisher

published in

• The Veterinary Journal  Journal

keywords

• Adrenergic Alpha-Antagonists
• Animals
• Body Temperature
• Cattle
• Cattle Diseases
• Endotoxemia
• Endotoxins
• Escherichia Coli
• Female
• Gastrointestinal Motility
• Heart Rate
• Muscle Contraction
• Muscle, Smooth
• Receptors, Adrenergic, Alpha-2
• Respiration
• Reticulum
• Rumen
• Yohimbine

Digital Object Identifier (DOI)

• 10.1016/s1090-0233(97)80066-4

start page

• 321

end page

• 327

volume

• 153

issue

• 3

URL

• http://dx.doi.org/10.1016/s1090-0233(97)80066-4