Solitary fibrous tumor of the tongue: report of a case with immunohistochemical and ultrastructural studies. Academic Article uri icon


  • Solitary fibrous tumors are rare in extrapleural sites and extremely rare in the oral cavity. We report a case of a solitary fibrous tumor arising from the tongue of a 70-year-old woman. The tumor measured 1.6 cm in maximum diameter and consists of spindle-shaped cells distributed in a haphazard pattern. Immunohistochemical studies show strong positivity for CD34 and bcl-2, and weak positivity for desmin. Smooth muscle actin and S-100 protein are negative. Electron microscopy shows uniform neoplastic spindle cells with mesenchymal features. The differential diagnosis for spindle cell neoplasms in the tongue is discussed.

published proceedings

  • Ann Diagn Pathol

author list (cited authors)

  • Wu, S. L., Vang, R., Clubb, F. J., & Connelly, J. H.

citation count

  • 21

complete list of authors

  • Wu, Sang Ling||Vang, Russell||Clubb, Fred J||Connelly, John H

publication date

  • January 2002