Solitary fibrous tumor of the tongue: report of a case with immunohistochemical and ultrastructural studies. Academic Article

abstract

• Solitary fibrous tumors are rare in extrapleural sites and extremely rare in the oral cavity. We report a case of a solitary fibrous tumor arising from the tongue of a 70-year-old woman. The tumor measured 1.6 cm in maximum diameter and consists of spindle-shaped cells distributed in a haphazard pattern. Immunohistochemical studies show strong positivity for CD34 and bcl-2, and weak positivity for desmin. Smooth muscle actin and S-100 protein are negative. Electron microscopy shows uniform neoplastic spindle cells with mesenchymal features. The differential diagnosis for spindle cell neoplasms in the tongue is discussed.

authors

• Clubb, Fred

published proceedings

• Ann Diagn Pathol

author list (cited authors)

• Wu, S. L., Vang, R., Clubb, F. J., & Connelly, J. H.

citation count

• 21

complete list of authors

• Wu, Sang Ling||Vang, Russell||Clubb, Fred J||Connelly, John H

publication date

• January 2002

publisher

• Elsevier  Publisher

published in

• Annals of Diagnostic Pathology  Journal

keywords

• Aged
• Biomarkers, Tumor
• Cell Nucleus
• Endoplasmic Reticulum, Rough
• Female
• Fibroma
• Humans
• Immunohistochemistry
• Neoplasm Proteins
• Tongue Neoplasms

Digital Object Identifier (DOI)

• 10.1053/adpa.2002.33903

start page

• 168

end page

• 171

volume

• 6

issue

• 3

URL

• http://dx.doi.org/10.1053/adpa.2002.33903