Novel medical device polymers: In vivo biodegradation and analytical and histopathological characterization Conference Paper uri icon


  • The data showed that while the rabbit tissues were exposed to degradation products of each type of polymer, there was no adverse tissue response. As expected, the higher the I2DT content in the polymer the faster the degradation, bulk erosion and resorption (70%I2DT 1 yr; 40%I2DT 2 yrs; 10%I2DT discs are expected to be nearly resorbed by 3.5 yrs). This study design allowed the authors to assemble a complete chronology of the histological, analytical and structural changes of 3 polymer formulations in a family of new medical device materials.

published proceedings

  • 8th World Biomaterials Congress 2008

author list (cited authors)

  • Zeltinger, J., Nesseler, E., Nichols, R., & Clubb, F. J.

complete list of authors

  • Zeltinger, J||Nesseler, E||Nichols, R||Clubb, FJ

publication date

  • December 2008