Correlating clinical activity and histopathologic assessment of gastrointestinal lesion severity: current challenges. Academic Article

abstract

• There has been increasing awareness that the severity of histopathologic lesions does not always correlate with the severity of clinical signs. Several grading systems for gastrointestinal histopathologic lesions have been generated, but there has been no widespread acceptance of one system. The World Small Animal Veterinary Association sponsored a gastrointestinal study group that produced a template of histologic changes in the gastrointestinal tract of the feline and canine in an attempt to generate widespread acceptance of a grading system. This article outlines the progress, pitfalls, and challenges in correlating histopathologic changes in the gastrointestinal tract with clinical activity.

authors

• Mansell, Karen

published proceedings

• Vet Clin North Am Small Anim Pract

author list (cited authors)

• Willard, M., & Mansell, J.

citation count

• 24

complete list of authors

• Willard, Michael||Mansell, Joanne

publication date

• January 2011

publisher

• Elsevier  Publisher

published in

• Veterinary Clinics of North America: Small Animal Practice  Journal

keywords

• Animals
• Biopsy
• Cat Diseases
• Cats
• Dog Diseases
• Dogs
• Pathology, Veterinary
• Severity Of Illness Index

Digital Object Identifier (DOI)

• 10.1016/j.cvsm.2011.01.005

start page

• 457

end page

• 463

volume

• 41

issue

• 2

URL

• http://dx.doi.org/10.1016/j.cvsm.2011.01.005