Expansion of the pig comparative map by expressed sequence tags (EST) mapping. Academic Article uri icon


  • We have used a PCR-based approach for the genetical and physical mapping of 34 transcripts isolated from a porcine small intestine cDNA library. All but one gene were regionally localized by using a somatic pig-rodent cell hybrid panel, and 12 genes were mapped by linkage analysis of single-stranded conformational polymorphisms developed in 3' untranslated regions of transcripts. For 20 of the transcripts, the human homolog has already been mapped. This study thus represents a significant contribution to the pig comparative map. Some important findings were that we could clarify the extent of a previously identified inversion event in a region of conserved synteny between SSC6q and HSA1p, that SSC14q does contain a region homologous to HSA1, a situation not clear from earlier ZOO-FISH studies, and that the homology between SSC17 and HSA20 includes the p-arm of HSA20.

published proceedings

  • Mamm Genome

author list (cited authors)

  • Fridolfsson, A. K., Hori, T., Winter, A. K., Fredholm, M., Yerle, M., Robic, A., Andersson, L., & Ellegren, H.

citation count

  • 25

complete list of authors

  • Fridolfsson, AK||Hori, T||Winterø, AK||Fredholm, M||Yerle, M||Robic, A||Andersson, L||Ellegren, H

publication date

  • December 1997