Genetic mapping of quantitative trait loci for growth and fatness in pigs. Academic Article

abstract

• The European wild boar was crossed with the domesticated Large White pig to genetically dissect phenotypic differences between these populations for growth and fat deposition. The most important effects were clustered on chromosome 4, with a single region accounting for a large part of the breed difference in growth rate, fatness, and length of the small intestine. The study is an advance in genome analyses and documents the usefulness of crosses between divergent outbred populations for the detection and characterization of quantitative trait loci. The genetic mapping of a major locus for fat deposition in the pig could have implications for understanding human obesity.

authors

• Andersson, Leif

published proceedings

• Science

altmetric score

• 7

author list (cited authors)

• Andersson, L., Haley, C. S., Ellegren, H., Knott, S. A., Johansson, M., Andersson, K., ... Hansson, I.

citation count

• 509

complete list of authors

• Andersson, L||Haley, CS||Ellegren, H||Knott, SA||Johansson, M||Andersson, K||Andersson-Eklund, L||Edfors-Lilja, I||Fredholm, M||Hansson, I

publication date

• March 1994

publisher

• American Association for the Advancement of Science (AAAS)  Publisher

published in

• Science  Journal

keywords

• Adipose Tissue
• Animals
• Chromosome Mapping
• Crosses, Genetic
• Disease Models, Animal
• Female
• Genes
• Genetic Markers
• Humans
• Intestine, Small
• Likelihood Functions
• Male
• Obesity
• Phenotype
• Swine

PubMed Central ID

• 8134840

Digital Object Identifier (DOI)

• 10.1126/science.8134840

start page

• 1771

end page

• 1774

volume

• 263

issue

• 5154

URL

• http://dx.doi.org/10.1126/science.8134840