Correspondence on Lovell et al.: identification of chicken genes previously assumed to be evolutionarily lost. Academic Article

abstract

• Through RNA-Seq analyses, we identified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes. These genes tended to cluster in GC-rich regions that have poor coverage in genome sequence databases. Hence, the occurrence of syntenic groups of vertebrate genes that have not been observed in Aves does not prove the evolutionary loss of such genes.Please see related Research article: http://dx.doi.org/10.1186/s13059-014-0565-1 and Please see response from Lovell et al: https://www.dx.doi.org/10.1186/s13059-017-1234-y.

authors

• Andersson, Leif

published proceedings

• Genome Biol

altmetric score

• 5.75

author list (cited authors)

• Bornelv, S., Seroussi, E., Yosefi, S., Pendavis, K., Burgess, S. C., Grabherr, M., Friedman-Einat, M., & Andersson, L.

citation count

• 36

complete list of authors

• Bornelöv, Susanne||Seroussi, Eyal||Yosefi, Sara||Pendavis, Ken||Burgess, Shane C||Grabherr, Manfred||Friedman-Einat, Miriam||Andersson, Leif

publication date

• June 2017

publisher

• Springer Nature  Publisher

published in

• n1474-760XISSN  Journal

keywords

• Animals
• Chickens
• Evolution, Molecular
• Humans
• Membrane Proteins
• Sequence Analysis, RNA
• Synteny
• Tumor Necrosis Factor-alpha

PubMed Central ID

• 28615067

Digital Object Identifier (DOI)

• 10.1186/s13059-017-1231-1

start page

• 112

volume

• 18

issue

• 1

URL

• http://dx.doi.org/10.1186/s13059-017-1231-1