A COD BASED REDUCTION ALGORITHM FOR BOOLEAN AND PROBABILISTIC BOOLEAN NETWORKS Conference Paper uri icon

abstract

  • We present a novel algorithm (CoDReduce) for reducing the size of a probabilistic Boolean network (PBN) model for genomic regulation. The algorithm uses the coefficient of determination (CoD) to find the best candidate for 'deletion' gene. The selection policy that determines how the transition probabilities for the reduced network are obtained from those in the original network is designed using the steady-state distribution (SSD) of the model. The performance of the algorithm is measured by the shift in the steady-state distribution after applying the mean-firstpassage- time (MFPT) control policy, and the relative effect of the selection policy on the MFPT control policy.

name of conference

  • 2009 IEEE International Workshop on Genomic Signal Processing and Statistics

published proceedings

  • 2009 IEEE International Workshop on Genomic Signal Processing and Statistics

author list (cited authors)

  • Ghaffari, N., Ivanov, I., & Dougherty, E.

citation count

  • 0

complete list of authors

  • Ghaffari, Noushin||Ivanov, Ivan||Dougherty, Edward

publication date

  • May 2009