The Effect of Static and Dynamic Loading on Degradation of PLLA Stent Fibers Conference Paper uri icon

abstract

  • PLLA is a commonly used biodegradable polymer in stent designs because it is non-toxic and easily eliminated from the body. However, very little is known about the effect of loading conditions on the degradation rate. Rajagopal and Wineman developed a model of polymer degradation which is driven by load applied to the fiber [1]. Soares et. al. further developed this model for use with PLLA stent fibers under tensile loading conditions [2]. In this model the degradation rate is linearly related to deformation through the radius in the (IB, IIB) plane. Both models predict that greater deformation will induce a higher degree of degradation.

name of conference

  • ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation

published proceedings

  • ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation

author list (cited authors)

  • Hayman, D., Bergerson, C., Miller, S., Moreno, M., & Moore, J. E.

citation count

  • 1

complete list of authors

  • Hayman, Danika||Bergerson, Christie||Miller, Samantha||Moreno, Michael||Moore, James E

publication date

  • September 2013