AAPS 2010. All rights reserved. Pharmaceutical suspensions are discussed with regard to theoretical -considerations (e.g., interfacial properties, electric double layer, wetting, flocculated and deflocculated systems), stability factors (e.g., settling and sedimentation, effect of particle size, crystal growth, and use of structured vehicles, etc.), and rheologic aspects. A thorough understanding of these aspects is important from a stability standpoint, as the stability of suspension systems depends both on the properties of the dispersed solid and on those of the vehicle.
