Characterization of a Wireless Potentiostat for Integration With a Novel Implantable Biotransducer Academic Article uri icon

abstract

  • Wireless potentiostats are being developed and commercialized for use in the development of implantable electrochemical biosensors for the monitoring of physiological markers in a wide range of pathologies.The merits and drawbacks of the Pinnacle 8151 dual potentiostat were investigated for use with a novel implantable biotransducer, the dual responsive microdisc electrode array (MDEA 5037) of ABTECH Scientific.The potentiostat was evaluated with R and RC dummy cells and with MDEA transducers modified with polypyrrole-poly(2-hydroxyethyl methacrylate) electroconductive hydrogels that were all qualified by calibrated ac impedance spectroscopy.In a laboratory setting, the 8151 potentiostat maintained a steady and unbroken signal as far away as 75 ft(23 m),and when unobstructed,up to 100 ft (30 m).The error between the two channels was determined to be 6.4(0.3) and 0.70.1% for resistor-capacitor dummy cells RC=nominally 10MOmega;and 1 mu;F and resistor dummy cells (R=nominally} 10 M) respectively.The intra-channel variability was judged to be too large for exacting analyte determinations. ©2013 IEEE.

author list (cited authors)

  • Kotanen, C. N., & Guiseppi-Elie, A.

citation count

  • 12

publication date

  • March 2014