Optimal design and control of a reactive distillation system Academic Article uri icon


  • This article presents the design and control of a reactive distillation system utilizing recent advances in mixed integer dynamic optimization. A high fidelity dynamic model is used to predict the behavior of the process under time-varying disturbances. Design and control decisions, involving both discrete and continuous variables, are simultaneously optimized leading to a more economically attractive and better controlled system than that obtained by following a sequential optimization approach. It is shown that the resulting design and control scheme can guarantee feasible operation under bounded uncertainty at a minimum total average cost, representing 17% savings over the original design.

published proceedings


author list (cited authors)

  • Panjwani, P., Schenk, M., Georgiadis, M. C., & Pistikopoulos, E. N.

citation count

  • 19

complete list of authors

  • Panjwani, P||Schenk, M||Georgiadis, MC||Pistikopoulos, EN

publication date

  • October 2005