Generalized modular framework for the synthesis of heat integrated distillation column sequences Academic Article uri icon


  • The synthesis of simple and Heat Integrated distillation column sequences is a challenging problem of high economic importance due to its structural and physical complexities and to its economic impact on chemical industries. In this paper this synthesis problem is addressed through a novel systematic superstructure representation method extending the principles of the Generalized Modular Framework (Papalexandri and Pistikopoulos, 1996. A.I.Ch.E. Journal 42 (4), 1010-1032). The method proposes systematic structural and physical models addressing the problem's inherent complexities, generating considerably compact optimization problems while avoiding the use of simplifying assumptions. The method employed for ternary and quaternary non-azeotropic separations is demonstrated over illustrating case studies obtaining the most energy efficient distillation column sequences and Heat Integration schemes and generating substantial energy savings. 2005 Elsevier Ltd. All rights reserved.

published proceedings


author list (cited authors)

  • Proios, P., Goula, N. F., & Pistikopoulos, E. N.

citation count

  • 19

complete list of authors

  • Proios, P||Goula, NF||Pistikopoulos, EN

publication date

  • September 2005