Model-based blood glucose control for Type 1 diabetes via parametric programming. Academic Article uri icon


  • An advanced model-based control technique for regulating the blood glucose for patients with Type 1 diabetes is presented. The optimal insulin delivery rate is obtained off-line as an explicit function of the current blood glucose concentration of the patient by using novel parametric programming algorithms, developed at Imperial College London. The implementation of the optimal insulin delivery rate, therefore, requires simple function evaluation and minimal on-line computations. The proposed framework also addresses the uncertainty in the model due to interpatient and intrapatient variability by identifying the model parameters which ensure that a feasible control law can be obtained. The developments reported in this paper are expected to simplify the insulin delivery mechanism, thereby enhancing the quality of life of the patient.

published proceedings

  • IEEE Trans Biomed Eng

altmetric score

  • 6

author list (cited authors)

  • Dua, P., Doyle, F. J., & Pistikopoulos, E. N.

citation count

  • 153

complete list of authors

  • Dua, Pinky||Doyle, Francis J||Pistikopoulos, Efstratios N

publication date

  • August 2006