Simultaneous Multi-Parametric Model Predictive Control and State Estimation with Application to Distillation Column and Intravenous Anaesthesia
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The objective of this paper is to implement simultaneous multi-parametric model predictive control (mp-MPC) and moving horizon estimation (MHE). The approach is tested on two different processes: the control of a high dimensional chemical process, the distillation column and the regulation of the depth of anaesthesia (DOA). Due to the high dimensionality of the distillation column, model order reduction techniques were used together with the simultaneous mp-MPC and MHE. The methods show good performances and a good behavior in dealing with the effect of noise and the presence of constraints. 2014 Elsevier B.V.