Offset-free explicit hybrid model predictive control of intravenous anaesthesia
Additional Document Info
2015 IEEE. The paper describes strategies for the control of intravenous depth of anaesthesia for the induction and maintenance phase, based on a detailed compartmental model composed of a pharmacokinetic and a pharma codynamic model. The system can be described in a piece-wise affine fashion, leading to a hybrid model predictive control problem, which is solved explicitly via the solution of a multi-parametric mixed integer quadratic programming problem. Two model predictive control strategies are presented: An explicit hybrid model predictive strategy and a robust explicit hybrid model predictive strategy that uses a robust reference tracking algorithm. The control strategies are successfully tested on a set of 7 patients.
name of conference
2015 IEEE International Conference on Systems, Man, and Cybernetics