Coumarin-Based Photodegradable Hydrogel: Design, Synthesis, Gelation, and Degradation Kinetics. Academic Article uri icon


  • The design, synthesis, and characterization of a new class of coumarin-based photodegradable hydrogels are reported. Hydrogel formation was achieved rapidly and efficiently under aqueous conditions using copper-catalyzed click chemistry, which afforded excellent control over the rate of network formation. Rapid photodegradation, to the point of reverse gelation, was observed using both 365 and 405 nm light, and micrometer-scale features were eroded using two-photon irradiation at wavelengths as long as 860 nm.

published proceedings

  • ACS Macro Lett

altmetric score

  • 6

author list (cited authors)

  • Azagarsamy, M. A., McKinnon, D. D., Alge, D. L., & Anseth, K. S.

citation count

  • 89

complete list of authors

  • Azagarsamy, Malar A||McKinnon, Daniel D||Alge, Daniel L||Anseth, Kristi S

publication date

  • January 2014